A factory at the end of each long bone
A child grows taller because long bones such as the thigh and shin keep getting longer. The lengthening doesn't happen everywhere along the shaft — it happens at a specific zone near each end called the epiphyseal plate, or growth plate. It is a layer of cartilage sandwiched between the bone's shaft and its cap.
- Resting cartilage cells sit nearest the bone's cap, holding the reserve.
- These cells divide and stack into neat columns, pushing the cap away from the shaft.
- The older cells swell, then die and leave a scaffold behind.
- Bone-forming cells move in and turn the scaffold into solid bone — so the shaft is now longer.
IGF-1 is the chief signal driving the dividing-and-stacking step, which is why the GH/IGF-1 axis from Guide 1 translates so directly into height. Thyroid hormone and, at puberty, the sex hormones tune the pace.
Why estrogen closes the door
Growth cannot continue forever. As puberty advances, estrogen — in both girls and boys — gradually exhausts the resting cartilage and lets bone fully replace the plate. When the cartilage is gone, the plate has fused (closed), and that bone can never grow longer again. This is true in both sexes: in boys much of the relevant estrogen comes from converting testosterone, which is why the same hormone that triggers the growth spurt also ends it.
Bone age and growth velocity
Because the plates mature in a predictable order, an X-ray of the hand and wrist reveals a child's bone age — how far along the skeleton is, regardless of birthday age. A 9-year-old with a bone age of 11 has already used up much of their growth runway; a 9-year-old with a bone age of 7 has more time left. Bone age is one of the most useful tools for predicting final adult height.
The other key number is growth velocity — how many centimeters a child gains per year. A single height on a chart can mislead, but the slope rarely lies. A child who was tracking along the 25th percentile and then slows to crossing downward through lines is sending a signal worth investigating, even if their absolute height still looks normal.