Neuroendocrinology & the Brain–Body Axis

Vagus Nerve

The vagus nerve is the longest of the twelve cranial nerves—the cables that run directly out of the brainstem rather than through the spinal cord—and the only one that wanders far past the head, all the way down into the chest and belly. Its name comes from the Latin word for "wandering," because it strays so far from home: branching out to the throat, heart, lungs, stomach, and much of the gut. Picture it as a thick, two-way phone line laid between the brain and your internal organs, constantly carrying messages in both directions so the two can keep each other informed.

Most of that traffic actually flows upward, from the organs to the brain: the vagus is the main reporter telling the brainstem how fast the heart is beating, how full the stomach is, how the lungs are doing. In the other direction, it carries the calming, "rest and digest" commands of the parasympathetic nervous system—the branch of the autonomic system that puts the body at ease—gently slowing the heartbeat, easing breathing, and stirring the gut to digest a meal. This makes the vagus a central player in the brain–body axis, the loop of signals by which mind and body shape each other; it is why a deep, slow breath can steady a racing heart, and why doctors can sometimes treat epilepsy or depression by sending tiny electrical pulses along this very nerve.

Roughly four-fifths of the vagus's fibers are sensory, carrying news from the body up to the brain rather than commands down to the organs—so it is far more a listener than a talker.

Also called
tenth cranial nervecranial nerve XCN X第十对脑神经第十對腦神經迷走神經