Gastrointestinal, Respiratory & Other Systems

bronchodilator

A bronchodilator opens up tightened airways so air can flow more freely, the way loosening a kinked hose lets water run again. In asthma or COPD the muscle around the airways contracts and narrows them; a bronchodilator relaxes that muscle to ease breathing and wheezing.

There are three main classes. Beta-2 agonists (salbutamol, formoterol) relax airway smooth muscle by activating beta-2 receptors. Antimuscarinic agents (ipratropium, tiotropium) block the parasympathetic signal that constricts airways. Methylxanthines such as theophylline have a weaker, more old-fashioned role. Bronchodilators come in short-acting forms for quick relief and long-acting forms for maintenance, and are usually delivered straight to the lungs by inhaler to act fast with fewer body-wide effects.

Bronchodilators relieve the muscle-tightening part of airway disease but do not treat the underlying inflammation, which is why in asthma they are paired with inhaled steroids rather than used alone. Over-reliance on a reliever inhaler is a warning sign of poorly controlled disease that needs review.

During an asthma flare a person inhales salbutamol and feels the chest tightness ease within minutes as the airways open.

Salbutamol is a short-acting beta-2 agonist used to quickly relieve bronchoconstriction.

Bronchodilators relax airway muscle but do not control the inflammation underlying asthma; relying on a reliever inhaler frequently signals undertreated disease.

Also called
airway dilator扩支气管药擴支氣管藥