coping with NP-completeness
Proving your problem is NP-complete feels like hitting a wall, but it is not the end of the road, it is a sign to change strategy. NP-completeness only says no FAST, EXACT, GENERAL algorithm is likely. In practice you almost never need all three of those at once. The field of coping with NP-completeness is the well-stocked toolbox of what you do instead, and real software solves NP-hard problems every day.
There are several proven escape routes, and the trick is knowing which to use. First, APPROXIMATION ALGORITHMS give a provably near-optimal answer fast, for example a tour within 1.5 times optimal for metric TSP, or a vertex cover within a factor of 2. Second, HEURISTICS and industrial SOLVERS (SAT solvers, integer-programming solvers) have no worst-case guarantee but routinely crush huge real instances, because real inputs rarely look like the contrived worst case. Third, PARAMETERIZED or fixed-parameter-tractable algorithms run fast when some parameter (like a vertex-cover size k) is small, isolating the exponential blow-up to that parameter alone. Fourth, many problems have TRACTABLE SPECIAL CASES: 2-SAT, colouring of bipartite graphs, problems restricted to trees or to planar inputs. Fifth, AVERAGE-CASE analysis and randomization can make typical instances easy even when the worst case is hard.
The honest framing is that NP-completeness sharpens, rather than ends, the engineering question. It tells you to abandon the hunt for a polynomial-time exact algorithm for the general case (because finding one would settle P versus NP) and instead choose deliberately: relax exactness, relax generality, exploit structure, or accept a probabilistic guarantee. Knowing a problem is NP-complete is therefore genuinely useful information: it stops you wasting effort on the impossible and points you at the toolbox that works.
Faced with NP-hard route planning, a delivery company does not give up. It runs a fast heuristic (nearest-neighbour plus local improvement) for a good-enough tour, or feeds the instance to an integer-programming solver that finds the provably optimal route for thousands of stops, because real road networks are far tamer than the worst case the theory warns about.
NP-complete is a signal to switch tools: approximate, use solvers/heuristics, exploit small parameters or special cases, not a dead end.
Approximation and FPT are not free lunches: many problems are even HARD TO APPROXIMATE (proven via the PCP theorem), and FPT only helps when the chosen parameter is genuinely small.