Cells of the Nervous System

axon hillock

The axon hillock is a small, cone-shaped bump on the body of a neuron — the cell that carries signals in your brain and nerves. Picture the neuron's main body as a round hub with many short branches reaching in; on one side, the hub narrows into a little ramp, and from the bottom of that ramp the single long output cable, called the axon, sets off. That tapering ramp is the axon hillock: the spot where the cell body hands off to the wire that carries its message away.

This little hump matters because it is the decision point. A neuron collects countless tiny nudges from its neighbors — some pushing it toward firing, some holding it back — and all of those nudges spread across the cell and pile up at the hillock. Here the membrane is unusually crowded with voltage-gated sodium channels, tiny gates that pop open when the electrical charge crosses a threshold. If the combined push is strong enough, the gates fly open and a full nerve signal, the action potential, ignites and races down the axon. So the axon hillock is the neuron's trigger: the place that adds up the votes and decides, moment by moment, whether to fire.

Strictly speaking, the action potential usually starts just past the hillock, in the first stretch of bare axon called the axon initial segment, but the two are so close that the hillock is commonly described as the firing point.

Also called
spike initiation zone轴突起始段附近区域軸突起始段附近區域