Cancer Chemotherapy & Immunopharmacology

antineoplastic

Antineoplastic literally means against new growth; a neoplasm is an abnormal, often cancerous, mass of cells. An antineoplastic is therefore any drug whose job is to stop or shrink that growth. Think of it as the umbrella term for the whole anticancer pharmacy, from old-fashioned chemotherapy to the newest precision medicines.

Under this single label sit very different mechanisms. Some antineoplastics are broadly cytotoxic, damaging DNA or division machinery in any fast-dividing cell. Others are highly selective: targeted small molecules that switch off a specific cancer-driving protein, antibodies that flag tumour cells, or immune drugs that unleash the patient's own T cells. What unites them is the goal, not the method.

The word is a category, not a guarantee of safety or success. Antineoplastics range from drugs with brutal, broad toxicity to ones with narrow, defined side effects. Choosing among them depends on the tumour type, its molecular features, and how much normal tissue the patient can spare.

Antineoplastic is often used interchangeably with anticancer drug; cytotoxic drug is narrower, referring mainly to the classic DNA- and division-damaging subset.

Also called
anticancer drug抗癌药抗癌藥